Impact of the arterial input function on microvascularization parameter measurements using dynamic contrast-enhanced ultrasonography

Table 4 Influence of the size of the arterial region of interest (in vivo experiments: Statistical analyses)

	Day of examination : P-ANOVA values
Semi-quantitative microvascularization parameters
PI	0.027
TPI	0.010
Slope of the WI	0.070
MTT	< 0.001
AUC	0.808
AUWI	0.562
AUWO	0.832
Quantitative microvascularization parameters
BF	< 0.001
BV	< 0.001
MTT	0.033

ANOVA: Analysis of variance; PI: Peak intensity; T_PI: Time to peak intensity; MTT: The mean transit time; AUC: The area under the curve; AUWI: The area under the wash-in; AUWO: The area under the wash-out; BF: The tissue blood flow; BV: The tissue blood volume.