Estimation of intra-operator variability in perfusion parameter measurements using DCE-US

Figure 6 The graph displays an example of a time intensity curve with 4 of its 7 associated perfusion parameters: the peak intensity or peak intensity (difference between V_max and V₀), the time to peak intensity or time to peak intensity (the difference between T_max and T_L), the slope coefficient of the wash-in (the slope of the tangent of the wash-in at half maximum) and the full width at half maximum or FWHM (corresponding to a first approximation of the mean transit time). The three other perfusion parameters extracted from the time intensity curve were the area under the curve, the area under the wash-in and the area under the wash-out. PI: Peak intensity; T_PI: Time to peak intensity.