Image of tumor metastasis and inflammatory lymph node enlargement by contrast-enhanced ultrasonography

Figure 4 The contrast-enhanced ultrasonography image and histopathological image of the acute inflammation-induced lymph node enlargement model. The model of inflammation-induced lymph node enlargement at 7 d after Escherichia coli was implanted (model 9). A: The enlarged popliteal lymph node with a diameter of 13 mm that was seen in the B mode ultrasound image. This lymph node showed up as a hypoechoic mass; B: Image of the popliteal lymph node that was imaged after the contrast agent was administered in the periphery of the primary lesion. The entire lymph node was imaged; C: Histopathological image (hematoxylin-eosin stain) of the lymph node that was extracted. Invasion of inflammatory cells, mainly nucleocytes, was seen. These are findings of acute lymphadenitis.