Contrast enhanced ultrasound of hepatocellular carcinoma

Table 2 Setting conditions of Sonazoid-enhanced US at a low and a high MI

Parameters	Low MI	High MI
Transducer	3.5 or 4.0-MHz convex transducer
Imaging mode	Coded phase inversion (A), Contrast pulse sequence (B), Pulse inversion harmonic (C), Amplitude modulation (D)	Coded harmonic angio (A)
MI	0.12-0.3 (average 0.2)	0.7-1.0 (average 0.8)
Frame rate	7-13 frames	2 -13 frames
Focus position	Bottom of the liver (A, D), Bottom of the lesion (B, C)	Bottom of the lesion (A)

A: LOGIQ 7 ultrasound system (GE Healthcare, Milwaukee, WI). Both imaging software programs consist of phase inversion harmonic and coded technology. These programs restrict signal components from tissues and emphasize signals from blood vessels; B: ACUSON Sequoia ultrasound system (Mochida Siemens Medical System, Tokyo, Japan); C: Aplio-XV ultrasound system (Toshiba, Tokyo, Japan); D: LOGIQ E9 ultrasound system (GE Healthcare, Milwaukee, WI).