Exploring new frontiers in molecular imaging: Emergence of 68Ga PET/CT

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Feb 28, 2010 (publication date) through Dec 23, 2024

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World Journal of Radiology

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1949-8470

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Radiol. Feb 28, 2010; 2(2): 55-67
Published online Feb 28, 2010. doi: 10.4329/wjr.v2.i2.55

Table 2 Examples of FDA approved monoclonal antibodies

Generic name	Target	Type	Indication
Rituximab	CD20	Chimeric IgG1	Non-Hodgkins lymphomas
Trastuzumab	HER-2/neu	Humanized IgG1	Breast cancer
Alemtuzumab	CD52	Humanized IgG1	Chronic lymphaocytic leukaemia
Bevacizumab	VEGF	Humanized IgG1	Colorectal cancer
			Non-small cell lung cancer
			Breast cancer
			Glioblastoma
			Renal cancer
Cetuximab	EGFR	Chimeric IgG1	Colorectal cancer
			Head and neck cancer
Panitumumab	EGFR	Human IgG1	Colorectal cancer
Ofatumumab	CD20	Human IgG1	Chronic lymphocytic leukaemia
Gemtuzumab Ozogamicin	CD33	Humanized IgG4 conjugated to calicheamicin	Acute myeloid leukaemia
⁹⁰Y-Ibritumomab Tiuxetan	CD20	⁹⁰Y-radiolabeled murine IgG1	Non-Hodgkins lymphoma
¹³¹I-Tositumomab	CD20	¹³¹I-radiolabeled murine IgG2a	Non-Hodgkins lymphoma

FDA: Food and Drug Administration; EGFR: Epidermal growth factor receptor; VEGF: Vascular endothelial growth factor.

Citation: Tan EH, Goh SW. Exploring new frontiers in molecular imaging: Emergence of ⁶⁸Ga PET/CT. World J Radiol 2010; 2(2): 55-67
URL: https://www.wjgnet.com/1949-8470/full/v2/i2/55.htm
DOI: https://dx.doi.org/10.4329/wjr.v2.i2.55