Plea to radiologists: Please consider Mahvash disease when encountering an enlarged pancreas

Table 1 Comparison of pancreas imaging features of Mahvash disease, diffuse pancreatic ductal carcinoma, diffuse pancreatic lymphoma, and autoimmune pancreatitis

Pancreas imaging features	Mahvash disease	Diffuse pancreatic ductal carcinoma	Diffuse pancreatic lymphoma	Autoimmune pancreatitis
Pancreatic size	Moderately to enormously enlarged	Slightly enlarged	Moderately enlarged	Moderately enlarged
Pancreas contour	Preserved	Lost (sausage-shaped)	Lost (sausage-shaped)	Lost (sausage-shaped)
Pancreas parenchyma	Normal	Hypo enhancing relative to normal pancreas	Hypo enhancing relative to normal pancreas	Hypo enhancing relative to normal pancreas
Pancreatic rim	No	Enhancing rim in some patients	No	Hypo enhancing rim
Pancreatic mass	None or single or multiple lesions	No	No	None or single or multiple enhancing lesions
Vascular involvement	No	Yes	Yes	Yes
Lymphadenopathy	No	Yes in some patients	Yes	Yes
Extra pancreatic organs involvement	No	No	No	Yes