Right-to-left shunt detection via synchronized contrast transcranial Doppler combined with contrast transthoracic echocardiography: A preliminary study

Figure 2 Brain magnetic resonance imaging revealing several infarcts located in the left occipital. A: Arrow, fluid-attenuated inversion recovery sequences and frontal lobes; B: Arrow, diffusion-weighted imaging, as well as in the subcortical white matter; C: Contrast transthoracic echocardiography shows 11–30 microbubbles both at rest and during the Valsalva maneuver (VM); D: The contrast transcranial Doppler only detects approximately five microbubbles after the VM.