Factors associated with gastrointestinal stromal tumor rupture and pathological risk: A single-center retrospective study

Table 1 Comparison of clinical data between unruptured and ruptured gastrointestinal stromal tumors

	Unruptured group (n = 38)	Rupture group (n = 12)	Statistical value	P value
Age (yr)	64.79 ± 9.75	57.17 ± 20.61	1.24	0.24
Gender			2.31	0.13
Male	19	9
Female	19	3
Pathological risk grade			8.47	0.02
Low risk	21	3
Intermediate risk	6	0
High risk	11	9
Tumor diameter (cm)	3.25 (2, 5.25)	9.0 (4.5, 13.63)	2.60	0.01
Tumor shape			17.56	< 0.01
Irregular	9	11
Regular	29	1
Internal necrosis			15.35	< 0.01
No	30	2
Yes	8	10
Gas-liquid interface			23.68	< 0.01
Absence	27	1
Presence	11	11
Primary site			0.23	0.63
Gastric	22	6
Small bowel	16	6
Mitotic count (50/HPF)	6.11 ± 2.60	6.17 ± 1.64	0.08	0.94
Ki-67 index (%)	5.50 (4.75, 8.00)	7.50 (5.00, 14.25)	1.15	0.25

HPF: High-power field.