Contrast-enhanced multidetector computed tomography features and histogram analysis can differentiate ameloblastomas from central giant cell granulomas

Table 4 Summary of radiographic, multidetector computed tomography and magnetic resonance imaging findings in central giant cell granulomas and ameloblastomas

	Ameloblastoma	CGCG
Radiography	Posterior mandible; unilocular or multilocular; scalloped margins; root resorption, root displacement and bone expansion- may erode the cortex	Central mandible; multilocular sclerotic; root resorption, root displacement and bony expansion and cortical erosion
CBCT or MDCT	Mixed solid and cystic or purely cystic with thick enhancing rim or enhancing nodule (in unicystic variant)	Avid enhancement of soft tissue; mineralised matrix; better bony details
Our findings	Unilocular 66.7%; lytic 60.6%; solid component shows isoenhancement compared to surrounding muscles 63%; no matrix mineralisation in 69.7%	Multilocular 58.3%; mixed lytic sclerotic 75%; solid component shows hyperenhancement compared to surrounding muscles 50%; matrix mineralisation in 83.3%
MRI	T1 weighted – isointense; T2 weighted – hyperintense- cystic component; Heterogenous solid component	T1 weighted isointense; T2 weighted hyperintense to heterogeneous solid component

CBCT: Cone beam computed tomography; CGCG: Central giant cell granulomas; MDCT: Multidetector computed tomography; MRI: Magnetic resonance imaging.