Diagnostic performance of abbreviated gadoxetic acid-enhanced magnetic resonance protocols with contrast-enhanced computed tomography for detection of colorectal liver metastases

Table 4 Comparison of diagnostic performance of three reading sessions including abbreviated magnetic resonance imaging protocol 2

	Reader 3						Reader 4
	Ab-MRI	Standard MRI	Ab-MRI + CE-CT	P value (Ab-MRI vs standard)	P value (Ab-MRI vs Ab-MRI + CE-CT)	P value (standard vs Ab-MRI + CE-CT)	Ab-MRI	Standard MRI	Ab-MRI + CE-CT	P value (Ab-MRI vs standard)	P value (Ab-MRI vs Ab-MRI + CE-CT)	P value (standard vs Ab-MRI + CE-CT)
Sensitivity	93.3 (90.7-95.0)	94.9 (92.7-95.9)	95.9 (93.8-96.9)	0.25	0.063	0.5	94.4 (90.1- 97.2)	95.9 (93.8-96.9)	96.9 (95.1-97.6)	0.25	0.063	0.5
Specificity	96 (93.1-97.8)	98.3 (95.9-99.4)	98.3 (96.0-99.4)	0.125	0.125	> 0.99	97.7 (94.3-99.4)	98.3 (96.0-99.4)	98.9 (96.8-99.7)	> 0.99	0.5	> 0.99
PPV	96.3 (93.6-98.0)	98.4 (96.2-99.4)	98.4 (96.3-99.4)	0.125	0.125	> 0.99	97.9 (94.6-99.4)	98.4 (96.3-99.4)	99 (97.1-99.7)	> 0.99	0.5	> 0.99
NPV	92.8 (90.0-94.6)	94.5 (92.2-95.6)	95.6 (93.3-96.6)	0.5	0.125	0.5	94 (89.4-96.9)	95.6 (93.3-96.6)	96.7 (94.7-97.5)	0.25	0.063	0.5
Accuracy	94.6 (91.9-96.3)	96.5 (94.2-97.5)	97 (94.9-98.0)	0.016	0.004	0.5	95.9 (93.4-97.7)	97 (94.9-98.0)	97.8 (95.9-98.6)	0.125	0.063	0.5
AUROC	0.947 (0.924-0.969)	0.943 (0.919-0.967)	0.948 (0.925-0.971)	0.603	0.862	0.156	0.960 (0.941-0.980)	0.971 (0.954-0.988)	0.979 (0.964-0.993)	0.045	0.007	0.083

Abbreviated magnetic resonance imaging protocol 2 consisting of fat-suppressed fast spin echo T2-weighted, diffusion-weighted, and hepatobiliary phase images. Numbers in square brackets represent 95%CIs. PPV: Positive predictive value; NPV: Negative predictive value; AUROC: Area under the receiver operating characteristic curve; Ab-MRI: Abbreviated magnetic resonance imaging; CE-CT: Contrast-enhanced computed tomography.