Diagnostic performance of abbreviated gadoxetic acid-enhanced magnetic resonance protocols with contrast-enhanced computed tomography for detection of colorectal liver metastases

Table 3 Comparison of diagnostic performance of three reading sessions including abbreviated magnetic resonance imaging protocol 1

	Reader 1						Reader 2
	Ab-MRI	Standard MRI	Ab-MRI + CE-CT	P value (Ab-MRI vs standard)	P value (Ab-MRI vs Ab-MRI + CE-CT)	P value (standard vs Ab-MRI + CE-CT)	Ab-MRI	Standard MRI	Ab-MRI + CE-CT	P value (Ab-MRI vs standard)	P value (Ab-MRI vs Ab-MRI + CE-CT)	P value (standard vs Ab-MRI + CE-CT)
Sensitivity	93.3 (88.9-96.4)	94.4 (92.3-95.1)	93.8 (91.8-94.6)	0.5	> 0.99	> 0.99	91.3 (88.9-92.5)	93.8 (91.7-94.8)	93.3 (91.1-94.3)	0.063	0.125	> 0.99
Specificity	97.1 (93.5-99.1)	98.9 (96.6-99.7)	98.9 (96.6-99.7)	0.125	0.25	> 0.99	97.7 (95.0-99.1)	98.3 (95.8-99.4)	98.3 (95.8-99.4)	> 0.99	> 0.99	> 0.99
PPV	97.3 (93.9-99.1)	98.9 (96.8-99.7)	98.9 (96.8-99.7)	0.25	0.25	> 0.99	97.8 (95.2-99.1)	98.4 (96.1-99.4)	98.4 (96.0-99.4)	0.25	0.25	> 0.99
NPV	92.9 (88.2-96.2)	94 (91.9-94.8)	93.5 (91.4-94.3)	0.5	> 0.99	> 0.99	91 (85.9-94.6)	93.5 (91.2-94.5)	93 (90.6-94.0)	0.063	0.125	> 0.99
Accuracy	95.1 (92.4-97.1)	96.5 (94.4-97.3)	96.2 (94.1-97.0)	0.063	0.125	> 0.99	94.3 (91.8-95.6)	95.9 (93.6-97.0)	95.7 (93.3-96.7)	0.031	0.063	> 0.99
AUROC	0.952 (0.931-0.974)	0.966 (0.948-0.984)	0.964 (0.945-0.982)	0.025	0.045	0.317	0.945 (0.922-0.968)	0.961 (0.941-0.980)	0.958 (0.938-0.978)	0.014	0.025	0.317

Abbreviated magnetic resonance imaging protocol 2 consisting of fat-suppressed fast spin echo T2-weighted, diffusion-weighted, and hepatobiliary phase images. Numbers in square brackets represent 95%CIs. PPV: Positive predictive value; NPV: Negative predictive value; AUROC: Area under the receiver operating characteristic curve; Ab-MRI: Abbreviated magnetic resonance imaging; CE-CT: Contrast-enhanced computed tomography.