Review on radiological evolution of COVID-19 pneumonia using computed tomography

Table 1 Characteristics and findings of the studies included in the systematic review

Ref.	Type of study	Patients included	Mean age in yr, range	CT scan follow-up	CT evaluation, scoring system
Han et al[9], 2020	Retrospective	17 surviving and discharged patients with COVID-19 pneumonia	40 ± 6	4 wk (4 weekly CT scan during hospitalization)	Semi-quantitative
Wang et al[10], 2020	Retrospective	63 patients with asymptomatic/mild, 378 with moderate, 43 with severe/critically COVID-19 pneumonia	47 (33-57)	From symptoms onset to beyond day 15	Quantitative
Liang et al[11], 2020	Retrospective	88 patients with mild COVID-19 pneumonia	42.7 (4-82)	3 wk after disease onset	Semi-quantitative
Sun et al[23], 2021	Case series	11 patients with severe COVID-19 pneumonia	52 (33-75)	CT scan during hospitalization (not well defined, at least 3 wk during hospitalization)	Qualitative
Zhou et al[12], 2020	Retrospective	100 patients with COVID-19 pneumonia (without ARDS)	52.3 ± 13.1 (27-80)	CT during hospitalization (from symptoms onset to beyond day 21)	Semi-quantitative
Wang et al[13], 2020	Retrospective	126 patients with COVID-19 pneumonia, (severe and critical cases excluded)	41.2 ± 10.8	CT scan during hospitalization (mean days of hospitalization 22 ± 5 d (12-40)	Qualitative
Wang et al[14], 2020	Retrospective	79 patients with non-severe (mild/common) COVID-19 pneumonia, 27 with severe pneumonia	48.0 ± 15.4	CT scan during hospitalization (mean days of hospitalization 25) + CT scan at 2-4 wk after discharge	Semi-quantitative
Zhang et al[15], 2020	Retrospective	33 patients with moderate COVID-19 pneumonia	49.0 ± 15.5	CT scan during hospitalization (mean days of hospitalization 20.8, range 18-37)	Semi-quantitative
Feng et al[16], 2020	Retrospective	19 patients with COVID-19 pneumonia	43.6 ± 15.5 (10-67)	0-34 d after symptoms onset	Quantitative
Liu et al[17], 2020	Retrospective	149 discharged patients with COVID-19 pneumonia (142 pneumonia, 7 severe pneumonia, no critical patients included)	43 (36-56)	Basal CT scan at discharge and at 1st, 2nd and 3rd week after discharge	Semi-quantitative
Pan et al[18], 2020	Retrospective	105 patients with COVID-19 pneumonia (severe pneumonia excluded)	48.6 ± 13.1 (23-72)	1-47 d after symptoms onset	Semi-quantitative
Zhuang et al[19], 2021	Retrospective	22 patients with COVID-19 pneumonia with solitary pulmonary lesion	40.7 ± 10.3 (23-54)	CT scan during hospitalization (mean days of hospitalization 19 d, range: 11-44) + first CT scan after discharge	Semi-quantitative
Urciuoli and Guerriero[24], 2020	Case series	6 patients with mild COVID-19 pneumonia	59.5	First CT on admission and 4 mo after symptoms onset	Qualitative
Zhang et al[20], 2020	Retrospective	53 patients with common COVID-19 pneumonia, 20 patients with severe COVID-19 pneumonia	45 ± 14 common pneumonia, 50 ± 15 severe pneumonia	0-30 d after symptoms onset	Quantitative
Pan et al[21], 2020	Retrospective	21 patients with COVID-19 pneumonia (severe pneumonia excluded)	40 ± 9 (25-63)	0-26 d after symptoms onset	Semi-quantitative
Wang et al[22], 2020	Prospective	90 patients with COVID-19 pneumonia	45 ± 14 (5-43)	0-24 d after symptoms onset	Semi-quantitative

ARDS: Acute respiratory distress syndrome; COVID-19: Coronavirus disease 2019; CT: Computed tomography.