Minireviews
Copyright ©The Author(s) 2021.
World J Radiol. Sep 28, 2021; 13(9): 283-293
Published online Sep 28, 2021. doi: 10.4329/wjr.v13.i9.283
Table 1 Summary of existing data surrounding the use of cardiac magnetic resonance imaging use in coronavirus disease 2019 patients
Ref.
Study design
Sample size
CMRI findings
Other diagnostic findings
Kariyanna et al[24],2020Systematic review of 9 case reports and 2 retrospective studies11 COVID-19 patients with reported myocardial inflammation or myocarditisLGE highlighted in 100% of the patientsElevated cardiac markers (Troponin, CK-MB, BNP) in 9 cases. Bilateral ground glass opacities seen in all patients with CT (6 cases). ECG abnormalities (ST-elevation and T-wave inversion) in 7 cases, and decreased LVEF in 6 cases. Active inflammation reported in the all biopsies performed (2 cases) and cardiomegaly reported in 7 cases
Puntmann et al[25], 2020Prospective observational cohort study100 recovered COVID-19 patientsRaised T1 in 73% of patients, raised T2 in 60%, LGE findings in 32%, and pericardial enhancement in 22% Elevated troponin in 71% of patients, and significantly elevated Troponin in 5%. Endomyocardial biopsy revealed active lymphocytic inflammation. Lower LVEF and RVEF noted
Huang et al[26], 2020Retrospective study26 recovered COVID-19 patients who reported cardiac symptoms and underwent CMRIElevated T2 and/or LGE in 58% (15 patients) with 14 patients having myocardial edema and 8 LGE +. Global T1, T2, and extracellular volume were elevated in patients with abnormal CMRIsDecreased RVEF, cardiac index, and stroke volume found in patients with positive CMRI findings
Clark et al[27], 2020Retrospective cohort analysis22 collegiate athletes with prior COVID-19 infectionLGE found in 9% (2 athletes)All patients had normal Troponin, normal ECG, normal LVEF. LV mass was higher and RVEF was lower in athletes compared to control group
Li et al[28], 2021Prospective observational cohort study40 COVID-19 patients with moderate to severe pneumonia and no cardiovascular medical historyLGE findings in 3% (1 patient), elevated extracellular volume values in 60% (24 patients)Normal LV and RV size and function. 70% (24 patients) had lower LV 2D-global longitudinal strain with subclinical changes of myocardial dysfunction