Multi-modality imaging of cardiac amyloidosis: Contemporary update

Table 3 Utilized acquisition parameters for ¹¹C-PiB, ¹⁸F florbetapir, and ¹⁸F florbetaben studies for cardiac amyloidosis[50-52]

Imaging considerations	Parameters
Patient and equipment preparation
Patient preparation	No prerequisites, no fasting
Position	Supine arms above shoulder or supported
Scan	Rest scan
Dose	11C-PiB 10-20 mCi (370-740 MBq) IV[50]
	18F florbetapir 6 mCi (222 MBq) IV[51]
	18F florbetaben 0.1 mCi/kg (4 MBq/kg) IV[52]
Time from injection to acquisition	11C-PiB 30 min[50]
	18F florbetapir continuous over 60 min[51]
	18F florbetaben continuous over 80 min[52]
Scan parameters
Field of view	Heart; Chest
Image type	Low-dose (10 mA, 120 kVp, free tidal breathing) CT scout scan
	Low-dose CT transmission scan (10 mA, 120 kVp, free tidal breathing) over the heart
	Emission scan 2D 40-60 mCi (1480-2220 MBq)
	Emission scan 3D 10-20 mCi (370-740 MBq)
Matrix	128 × 128-400 × 400
Reconstruction	Filtered back projection or iterative reconstruction

CT: Computed tomography.