Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging

Table 2 Positron emission tomography/magnetic resonance imaging results by group

	Group 1: Cardiovascular risk[15] (n = 62)	Group 2: Cocaine users (n = 13)		Group 3: Healthy controls (n = 10)	Group 2 and 3 difference [Sig. (ANCOVA)]
PET results
Target-to-Background ratios (TBR max)
Left	NA		1.77 ± 0.10	1.77 ± 0.07	F (1, 20) = 0.3, P = 0.619
Right	NA		1.93 ± 0.09	1.76 ± 0.04	F (1, 20) = 1.9, P = 0.178
R+L	NA		1.85 ± 0.09	1.76 ± 0.05	F (1, 20)= -0.2, P = 0.687
Most diseased segment
Left	NA		2.05 ± 0.15	1.99 ± 0.09	F (1, 20) = 0.0, P = 0.914
Right	NA		2.10 ± 0.10	1.93 ± 0.07	F (1, 20) = 1.3, P = 0.259
R+L	NA		2.07 ± 0.11	1.96 ± 0.08	F (1, 20) = 0.4, P = 0.560
MR results
Wall thickness (mm; mean, SE)
Left	NA		1.53 ± 0.06	1.25 ± 0.04	F (1, 20) = 7.6, P = 0.012
Right	NA		1.50 ± 0.07 1	1.20 ± 0.05	F (1, 19) = 8.3, P = 0.009
R+L	1.27 ± 0.04; t(12)2 = 4.12, P = 0.001		1.51 ± 0.062	1.22 ± 0.04 3	F (1, 20) = 100, P = 0.005
Wall area (mm2)
Left	NA		35.67 ± 2.25	29.02 ± 1.54	F (1, 20) = 3.3, P = 0.086
Right	NA		34.51 ± 2.061	27.37 ± 1.43	F (1, 19) = 4.9, P = 0.039
R + L	32.28 ± 1.43; t(9)4 = -3.13, P = 0.012		35.18 ± 1.95 5	28.19 ± 1.314	F (1, 20) = 4.9, P = 0.039

¹n = 12.

²Cocaine users > Cardiovascular risk: P < 0.001.

³Cardiovascular disease risk and healthy controls group difference: t(9) = -1.12, P = 0.294.

⁴Cardiovascular risk > healthy controls: P < 0.05.

⁵Cocaine users and Cardiovascular risk group difference: t(12) = 1.49, P = 0.163. NA: Not available.