Role of advanced magnetic resonance imaging in the assessment of malignancies of the mediastinum

Figure 8 Different diffusion weighted imaging approaches to an aggressive middle mediastinal mass. A 56 year-old woman with esophageal leiomyosarcoma stage IV. A-F: Restrictive behavior of the mass could be seen [Apparent diffusion coefficient (ADC): 0.951 × 10^-3 m²/s; malignant origin]. Derived biomarkers of three different ways of quantification of diffusion-weighted imaging (white asterisk) of the mass are shown: A-B: Mono-exponential approach (A: High b value; B: ADC map); C-D: bi-exponential scheme (Intravoxel incoherent motion; C: Perfusion fraction map; D: Diffusion coefficient map); E-F: Diffusion kurtosis imaging (E: Apparent diffusional kurtosis map; F: Apparent diffusion map). ADC: Apparent diffusion coefficient.