Role of advanced magnetic resonance imaging in the assessment of malignancies of the mediastinum

Figure 7 Multiparametric functional chest magnetic resonance of central lung cancer. A 78 year-old male with a central hilar mass in keeping with epidermoid type lung carcinoma. A and B: High b value (b = 1000 s/mm²) and apparent diffusion coefficient (ADC) map (B) revealing a heterogeneous and restrictive behavior of the lesion, related to hypercellularity and aggressiveness (white arrows on A and B). The mean ADC was 0.97 × 10^-3 mm²/s, confirming a malignant origin; C: Dynamic contrast-enhanced magnetic resonance showing a significant uptake of gadolinium based contrast agent on area under the curve parametric map (white asterisk), with central necrosis (White arrow on C); D: Time intensity curve (TIC) plot revealing steep slope of enhancement with posterior plateau (type B TIC) also favoring a malignant etiology. DCE-MR: Dynamic contrast-enhanced magnetic resonance; ADC: Apparent diffusion coefficient; TIC: Time intensity curve.