Susceptibility weighted imaging: Clinical applications and future directions

Table 5 Increased iron levels in the central nervous system

Entity	Increased iron location	Ref.
Parkinson’s disease	SN, pars compacta, brainstem	[53]
Alzheimer’s disease	Hippocampus, GP	[54]
PKAN	GP, SN sparing DN	[55]
Infantile neuroaxonal dystrophy	GP, SN, DN	[55]
Neuroferritinopathy	GP, P, DN with cavitation	[55]
Aceruloplasminemia	BG, thalami with no cavitation	[55]
Huntington’s disease	CN, P	[56]
Progressive MCI versus stable MCI	Right GP, SN	[57]
Multiple sclerosis	CN, P and thalamic pulvinar	[60]

CN: Caudate nucleus; GP: Globus Pallidus; P: Putamen; BG: Basal Ganglia; SN: Substantia Nigra; DN: Dentate nucleus; PKAN: Pantothenate kinase-associated neurodegeneration.