High-resolution computed tomography findings in humoral primary immunodeficiencies and correlation with pulmonary function tests

Table 3 Distribution of high-resolution computed tomography-detected airway abnormalities according to the severity of obstructive defect at pulmonary function tests in the overall study population, and results of logistic regression analysis for prediction of moderate-to-severe obstructive defects at PFTs n (%)

Abnormality	Absent	Mild	Moderate	Severe	Univariate analysis	Multivariate analysis
	n = 29	n = 12	n = 9	n = 2	P-value	P-value (odds ratio)
Bronchiectasis	19 (66.5)	9 (75)	7 (77.8)	1 (50)	NS	NS
Airway wall thickening	20 (69)	9 (75)	6 (66.7)	2 (100)	NS	NS
Tree-in-bud	2 (6.9)	2 (16.7)	5 (55.6)	1 (50)	0.0014	0.0027 (18.75)
Mucus plugging	8 (27.6)	8 (66.7)	5 (55.6)	2 (100)	0.0112	NS

NS: Non-significant.