Utility and correlation of known anticoagulation parameters in the management of pediatric ventricular assist devices

Table 2 Distribution of values for various measures of coagulation status

Test	n	Minimum	Maximum	mean	SD
Prothrombin time	97	12.5	30.8	14.542	2.34
Activated partial thromboplastin time (s)	98	26.1	200	79.779	44.62
INR	98	0.9	3	1.132	0.25
Anti-Xa levels (U/mL)	97	0.05	1.2	0.4381	0.24
TEG-R (min)	102	5.2	82.8	32.464	19.77
TEG-alpha angle	99	5.9	71.8	28.83	18
TEG-MA	98	10	75	46.002	18.08
TEG R (heparinase) (min)	102	5.1	34.5	8.455	3.2
TEG-K (heparinase)	102	0.8	12	2.029	1.12
TEG-α angle (heparinase)	102	17.8	74.4	63.306	7.3
TEG-MA (heparinase)	102	45.1	73	59.696	6.03
TEG-G (heparinase)	100	4.1	13.5	7.712	2.01
Platelet inhibition-ADP (%)	90	0	100	41.113	33.73
Platelet inhibition-AA (%)	91	0	100	43.69	37.05
Platelet count (k/μL)	131	77	451	267.05	89.6
Platelet volume	121	6.8	10.1	8.46	0.69
Heparin dose (units/kg per hour)	131	15	46	33.66	7.15

Summary of data are presented as number of individual data points (n) with value ranges, mean value and standard deviation given. TEG values without heparinase are represented by R (reaction time), ANGLE (alpha-angle), MA (mean amplitude). TEG values with heparinase are noted as RHEP, KHEP (K = coagulation time), ANGLEHEP, MAHEP and GAHEP (GA = overall clot strength). Percent of platelet inhibition via the AA and ADP pathways are shown. The range of administered heparin dose at the time of laboratory value collection is also presented. AA: Arachidonic acid; ADP: Adenosine phosphate; PT: Prothrombin time; aPTT: Activated thromboplastin time; INR: International normalized ratio.