Combined assessment of myocardial damage and electrical disturbance in chronic heart failure

Table 2 Univariate and multivariate analyses for cardiovascular events

	HR	95%CI	P value
Univariate analysis
Age, per 10-yr increase	1.297	1.105-1.524	0.0016
Female gender	0.829	0.573-1.199	0.3183
NYHA functional class II and III vs IV	1.960	1.381-2.747	0.0003
Atrial fibrillation	1.256	0.865-1.824	0.2304
Diabetes mellitus	1.103	0.758-1.605	0.6062
Dyslipidemia	0.958	0.635-1.447	0.8417
Hypertension	0.986	0.667-1.457	0.9459
BNP, per 1SD increase	1.166	1.019-1.334	0.0249
eGFR, per 1SD increase	0.589	0.467-0.733	< 0.0001
LV end-diastolic diameter, per 1SD increase	1.062	0.877-1.280	0.5272
LV ejection fraction, per 1SD increase	0.881	0.734-1.074	0.1998
Heart rate, per 1SD increase	0.869	0.724-1.062	0.1724
High H-FABP (> 4.5 ng/mL)	2.994	1.996-4.504	< 0.0001
QRS prolongation (≥ 120 ms)	1.897	1.264-2.832	0.0019
Multivariate analysis
Age, per 10-yr increase	1.093	0.921-1.298	0.3055
NYHA functional class II and III vs IV	1.55	1.055-2.309	0.0262
BNP, per 1SD increase	0.948	0.811-1.151	0.7003
eGFR, per 1SD increase	0.733	0.571-0.938	0.0144
High H-FABP (> 4.5 ng/mL)	1.745	1.088-2.793	0.0210
QRS prolongation (≥ 120 ms)	1.612	1.060-2.451	0.0258

HR: Hazard ratio; SD: Standard deviation; BNP: Brain natriuretic peptide; eGFR: Estimated glomerular filtration rate; NYHA: New York Heart Association.