Contrast use in relation to the arterial access site for percutaneous coronary intervention: A comprehensive meta-analysis of randomized trials

Table 1 Characteristics of included trials

Ref.	Year	TRA (n)	TFA (n)	Mean contrast volume (mL)		TRA operator experience	Patient population
				TRA	TFA
Mann et al[13]	1996	73	75	138	119	NR	ACS
Saito et al[14]	2003	77	72	180	186	Experienced	AMI
Reddy et al[15]	2004	25	50	123	135	Low	Elective PCI
Brasselet et al[4]	2007	57	57	97	91	Intermediate-experienced	ACS
Achenbach et al[5]	2008	152	155	88	79	Experienced	ACS, Elective PCI
Sentas et al[16]	2009	335	335	84	89	Experienced	ACS, Elective PCI
Chodór et al[17]	2009	50	50	198	197	Experienced	STEMI
Vazquez-rodriguez et al[18]	2009	217	222	275	281	Experienced	AMI
Chodór et al[19]	2011	49	59	165	162	Experienced	STEMI
Wang et al[20]	2012	60	59	160	164	Experienced	STEMI
Bernat et al[3]	2012	348	359	170	182	Experienced	STEMI
Michael et al[7]	2013	63	63	171	142	Experienced	NSTEMI or elective PCI with previous CABG
Kołtowski et al[11]	2014	52	51	63	65	Experienced	STEMI

ACS: Acute coronary syndrome; AMI: Acute myocardial infarction; CABG: Coronary artery bypass graft; NSTEMI: Non-ST-elevation myocardial infarction; PCI: Percutaneous coronary intervention; STEMI: ST-elevation myocardial infarction; TRA: Trans-radial access; TFA: Trans-femoral access.