Coronary artery disease detection - limitations of stress testing in left ventricular dysfunction

Table 1 Comparative analysis of the sensitivity, specificity and diagnostic accuracy for coronary artery disease detection using various imaging modalities¹

Modality	Sensitivity	Specificity	Positive predictive value	Negative predictive value	Diagnostic accuracy
SPECT	80%-100%	40%-50%	90%-95%	90%-95%	75%-80%
DSE	80%-85%	60%-80%	80%-90%	45%-60%	75%-80%
PET	85%-90%	80%-85%	85%-90%	80%-95%	80%-85%
CCT	70%-90%	85%-90%	90%-95%	90%-95%	90%-95%
CMR	95%-100%	90%-95%	90%-95%	90%-95%	95%-100%

¹This data is limited as it includes both patients with and without left ventricular dysfunction. DSE: Dobutamine stress echocardiography; SPECT: Single photon emission computerized tomography; PET: Positron emission tomography; CCT: Coronary computerized tomography; CMR: Cardiac magnetic resonance imaging.