Cardiovascular magnetic resonance imaging assessment of outcomes in acute myocardial infarction

Table 7 Cardiovascular magnetic resonance studies illustrating the prognostic importance of infarct in acute myocardial infarction

Ref.	Year	n	LGE method	Main findings	CMR timepoint	Follow-up
Husser et al[96]	2013	250	> 2SD	Extent of transmural infarction (no. of segments > 50% transmurality) only IP for MACE at 6 mo	7 d	163 wk
Izquierdo et al[97]	2013	440	> 2SD	IS was IP for AACEs (arrhythmic cardiac events: Sudden death, VT, VF, ICD shock) in model including LVEF, hypertension	7 d	123 wk
Eitel et al[34]	2011	208	> 5SD	IS was IP of MACE at 19 mo in model including MVO, LVEF, MSI, Killip, TIMI post-PPCI	3 d	18.5 mo
Miszalski-Jamka et al[98]	2010	77	Manual	LV transmurality index IP (HR 1.03) and IS (HR 1.03) IPs for MACE in a model containing RVEF and RV IS	“3-5 d”	1150 d
Larose et al[67]	2010	103	FWHM	IS strongest IP for MACE (HR 1.36) in model containing LVEF, CK. LGE > 23% had HR 6.1 for MACE	4.5 h	2 yr
Bodi et al[38]	2009	214	> 2SD	Extent of transmural infarction (no. of segments > 50% transmurality) IP for MACE (HR 1.35 if > 5 segs)	7 d	553 d
Wu et al[99]	2008	122	Manual	IS only IP of 2 yr MACE in model containing LVEF, LVESVI	2 d	538 d

LGE: Late gadolinium enhancement; FWHM: Full-width half-maximum; SD: Standard deviations; MACE: Major adverse cardiovascular events; LVEF: Left ventricular ejection fraction; PPCI: Primary percutaneous coronary intervention; LGE method (LGE quantification method): SD: Standard deviations; FWHM: Full-width half-maximum.