Cardiovascular magnetic resonance imaging assessment of outcomes in acute myocardial infarction

Table 2 Studies illustrating the prognostic importance of left ventricular volumes and adverse left ventricular remodelling in acute myocardial infarction

Ref.	Year	n	Modality	Main findings	Follow-up
Ahn et al[13]	2013	135	Echo	Adverse LV remodelling (> 20% inc. LVEDV) at 6 mo was IP 3 yr MACE. MACE rate approximately 25% in patients with adverse LV remodelling vs approximately 6% in non-remodelled patients	981 d
Hombach et al[6]	2005	110	CMR	Baseline LVEDV was IP for MACE (P = 0.038)	225 d
St John Sutton et al[39]	2003	512	Echo	Percentage change in LV area (surrogate for LV volume) between baseline echo and follow-up at 12 mo was IP for ventricular ectopy and VT	24 mo
Bolognese et al[12]	2002	284	Echo	Baseline LVESV was IP for cardiac death and MACE. Components of MACE higher in patients with adverse remodelling (> 20% inc. LVEDV: Mortality 14% vs 5%, MACE 18% vs 10%)	5 yr
Otterstad et al[40]	2001	712	Echo	Increase in LVESV between acute scan at 7 d and echo at 3 mo strongest IP for MACE	24 mo
St John Sutton et al[41]	1994	512	Echo	LV end-diastolic area (RR 1.1) and LV end-systolic area (RR 1.1) on baseline echo, and %-change in LV area at 12 mo echo (RR 1.55) were strongest IPs for MACE	12 mo
White et al[30]	1987	605	LV gram	LVESV of LV gram at 4 wk was strongest IP of long-term mortality (P < 0.0001)	78 mo

MACE: Major adverse cardiovascular events; IP: Independent predictor; LVEDV: Left ventricular end-diastolic volume; LVESV: Left ventricular end-systolic volume; Modality: Modality of LV volume assessment (CMR: Cardiovascular MRI; Echo: Echocardiography; LV gram: LV contrast angiography).