Cardiovascular magnetic resonance imaging assessment of outcomes in acute myocardial infarction

Table 12 Temporal changes in cardiovascular magnetic resonance-derived area at risk and myocardial salvage index in acute myocardial infarction

Ref.	Year	n	CMR timepoints post STEMI	AAR, IS method	Main findings
Mather et al[18]	2011	48	2 d → 1 wk → 30 d → 3 mo	> 2SD STIR, > 2SD LGE	AAR reduction at successive timepoints, 1-3 mo (-75%). No change MSI at d2 or 1 wk as IS and AAR decreased proportionally
Dall’Armelina et al[21]	2011	30	2 d → 1 wk → 2 wk → 6 mo	> 2SD T2p-BB, > 2SD LGE	100% had oedema at d2. AAR stable over 1st week (37% vs 39% LVM). Decreased by 2 wk and nearly resolved at 6 mo
Carlsson et al[138]	2009	16	1 d → 1 wk → 6 wk → 6 mo	Manual STIR, and LGE	AAR at all timepoints. AAR stable in 1st week, correlated with 1 wk SPECT. Decrease by 1 mo (10% LVM), nearly gone by 6 mo
Ripa et al[5]	2007	58	2 d → 1 mo → 6 mo	Manual STIR and LGE	All had oedema at d2. AAR decreased at all time points. No data on MSI in this study

AAR: Area at risk; MSI: Myocardial salvage index; AAR, LGE method: SD: Standard deviations; STIR: T2-weighted short-tau inversion recovery imaging; T2p-SS-BB: T2-prepared single-shot bright-blood; 3T: 3.0 tesla field strength; IS: Infarct size.