Copyright
©The Author(s) 2017.
World J Cardiol. Dec 26, 2017; 9(12): 830-837
Published online Dec 26, 2017. doi: 10.4330/wjc.v9.i12.830
Published online Dec 26, 2017. doi: 10.4330/wjc.v9.i12.830
Newcastle-Ottawa scale for bias assessment for case-controlled studies | ||
Newcastle-Ottawa scale for bias assessment | Cariou et al[9], 2008 | Grmec et al[10], 2009 |
Selection | 3 | 2 |
Comparability | 2 | 2 |
Exposure | 3 | 3 |
Cochrane Risk of Bias tool for the Randomized controlled study (Cariou et al[11]) | ||
Entry | Judgement | Support for judgement |
Random sequence generation (selection bias) | Low risk | Quote: “Patients were randomly assigned in a 1:1 ratio to the intervention or the control group” |
Allocation concealment (selection bias) | Low risk | Quote: “Randomization was performed centrally with the use of a computer-generated assignment sequence Intervention assignments were made in permuted blocks of varying size and were stratified according to site” |
Blinding of participants and personnel (performance bias) | High risk | Comment: Probably done |
Quote: “Single-blinded”; “physicians performing neurological follow-up and final outcome measurement, as well as study administrators and statisticians, were unaware of the intervention assignments” | ||
Comment: Probably done. However, only single blinding performed | ||
Blinding of outcome assessment (detection bias) (patient-reported outcomes) | Low risk | Quote: “Single-blinded” |
Comment: Probably done | ||
Blinding of outcome assessment (detection bias) (mortality) | Low risk | Obtained from medical records; Quote “CPC was assessed by face-to-face contact with patients still hospitalized, and through phone interviews in discharged patients using a standardized protocol” |
Review authors do not believe this will introduce bias | ||
Incomplete outcome data addressed (attrition bias) (Longer-term outcomes, > 6 wk) | Low risk | 60 d: 1/234 missing from intervention group (“lost to follow-up”); 0/242 missing from control group |
Selective reporting (reporting bias) | Low risk | A single scale to assess neurological outcomes was used and reported (CPC score) |
- Citation: Chaudhary R, Garg J, Krishnamoorthy P, Bliden K, Shah N, Agarwal N, Gupta R, Sharma A, Kern KB, Patel NC, Gurbel P. Erythropoietin therapy after out-of-hospital cardiac arrest: A systematic review and meta-analysis. World J Cardiol 2017; 9(12): 830-837
- URL: https://www.wjgnet.com/1949-8462/full/v9/i12/830.htm
- DOI: https://dx.doi.org/10.4330/wjc.v9.i12.830