Copyright
©The Author(s) 2016.
World J Cardiol. Feb 26, 2016; 8(2): 114-119
Published online Feb 26, 2016. doi: 10.4330/wjc.v8.i2.114
Published online Feb 26, 2016. doi: 10.4330/wjc.v8.i2.114
Study design | Population | PUFA administration | PUFA quantification | AF diagnosis | Results |
Prospective cohort[5] | 4815 individuals; age 72.8 yr; United States | Broiled/backed fish assessment. FU: 12 yr | FFQ | Annual ECG; hospital discharge diagnoses | Lower AF risk of 31% with fish intake ≥ 5 times/wk vs < 1/mo. P = 0.008 |
Prospective cohort[12] | 2174 subjects; mean age: 52.8 yr; Finland | Serum EPA and DHA and dosage. FU: 17.7 yr | DHA, EPA serum dosage | National computerized hospitalization registry | Lower AF risk of 38% for higher DHA levels. P = 0.02 |
Prospective cohort[6] | 3326 subjects; age: 74.1 yr; United States | Serum EPA, DHA dosage | DHA, EPA serum dosage | Annual ECG; telephonic contact 2/yr; hospitalizations | Lower AF risk for top vs lowest quartile of PUFA/ DHA levels |
Population study[7] | 3242 subjects affected by acute myocardial infarction; age: 54.1 yr; Italy | Previous PUFA intake vs not. FU: 360 d | FFQ | AF episodes during hospitalization | Lower risk of AF with fish oil |
Prospective cohort[8] | 47949 subjects; age: 46 yr; Denmark | Fish-oil intake assessment. FU: 5.7 yr | FFQ | Danish national hospitalization registry | Higher AF risk for top vs lowest quintiles of fish intake |
Prospective cohort[9] | 5184 subjects; age 67.4 yr; the Netherland | Fish-oil intake assessment. FU: 6.4 yr | FFQ | Two ECGs during FU; clinical data from general practitioners | No AF risk reduction in the highest tertile of fish intake |
Prospective cohort[10] | 44720 female; age: 63 yr; United States | Fish intake assessment. FU: 6 yr | FFQ | ECG at baseline and at the third and sixth years | No lower AF risk for higher fish intake |
Prospective cohort[11] | 4526 individuals; age: 62 yr; United States | Fish intake assessment. FU: 4 yr | FFQ | Two ECGs every 4 yr of FU; hospitalizations | No AF risk reduction in the top vs the lowest tertile of fish intake |
Post-hoc analysis of a RCT (Aleksova)[13] | 5835 systolic heart failure-subjects | N-3 PUFAs 1 g/d vs placebo; FU 3.9 yr | No PUFA dosage | ECG during FU visits | No AF risk reduction with n-3 PUFA |
- Citation: Martino A, Pezzi L, Magnano R, Salustri E, Penco M, Calo’ L. Omega 3 and atrial fibrillation: Where are we? World J Cardiol 2016; 8(2): 114-119
- URL: https://www.wjgnet.com//full/v8/i2/114.htm
- DOI: https://dx.doi.org/10.4330/wjc.v8.i2.114