Genetics of coronary artery disease and myocardial infarction

doi:10.4330/wjc.v8.i1.1

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Jan 26, 2016; 8(1): 1-23
Published online Jan 26, 2016. doi: 10.4330/wjc.v8.i1.1

Table 1 Heterogeneities in coronary artery disease/myocardial infarction

Clinical manifestation	Underlying pathology	Pathological processes of atherosclerosis
Asymptomatic stenosis Stable or unstable angina pectoris Silent MI Acute MI (NSTEMI and STEMI) Sudden cardiac death	Atheroma positive remodeling Atheroma negative remodeling Plaque rupture/thrombosis Critical stenosis/thrombosis Embolization Spontaneous dissection Anomalous origin/course Coronary spasm Myocardial bridging	Endothelial injury Lipid deposition Oxidative stress/response Inflammation Cellular proliferation/apoptosis Foam cell formation Matrix deposition/degradation Plaque rupture/hematoma/thrombosis Neovascular formation

MI: Myocardial infarction.

Citation: Dai X, Wiernek S, Evans JP, Runge MS. Genetics of coronary artery disease and myocardial infarction. World J Cardiol 2016; 8(1): 1-23
URL: https://www.wjgnet.com/1949-8462/full/v8/i1/1.htm
DOI: https://dx.doi.org/10.4330/wjc.v8.i1.1