Copyright
©The Author(s) 2015.
World J Cardiol. May 26, 2015; 7(5): 238-242
Published online May 26, 2015. doi: 10.4330/wjc.v7.i5.238
Published online May 26, 2015. doi: 10.4330/wjc.v7.i5.238
Figure 1 Structure and polypharmacology of quinazoline-based α1-adrenoceptor antagonists doxazosin, prazosin and terazosin in cardio-oncology.
MDR: Multidrug resistance; EGFR: Epidermal growth factor receptor; FGFR-2: Fibroblast growth factor receptor-2; HIF-1α: Hypoxia-inducible factor 1α; mTOR: Mammalian target of rapamycin; PDK1: 3-phosphoinositide-dependent protein kinase 1; TGF: Transforming growth factor.
- Citation: Patanè S. Insights into cardio-oncology: Polypharmacology of quinazoline-based α1-adrenoceptor antagonists. World J Cardiol 2015; 7(5): 238-242
- URL: https://www.wjgnet.com/1949-8462/full/v7/i5/238.htm
- DOI: https://dx.doi.org/10.4330/wjc.v7.i5.238