Effective treatment of depression improves post-myocardial infarction survival

doi:10.4330/wjc.v7.i4.215

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Apr 26, 2015 (publication date) through Jul 27, 2024

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Apr 26, 2015; 7(4): 215-223
Published online Apr 26, 2015. doi: 10.4330/wjc.v7.i4.215

Table 1 Summary of demographic biological, social, and psychological characteristics of depressed post-myocardial infarction patients treated for depression and comparison of those with treatment resistant and non treatment resistant depression (n = 770) n (%)

Characteristics	Treated DepressedPost-MI¹	TRDn = 103¹	Non TRDn = 667¹
Demographics and biological characteristics
Age, mean (SD), yr	59.2 (12.0)	57.0 (11.7)	59.5 (12.0)	t = -2.07, P = 0.04
Gender, female	365 (47.4)	59 (57.3)	306 (45.9)	χ² (1) = 4.65, P = 0.031
Ethnicity, minority	239 (31.0)	32 (31.1)	207 (31.0)	χ² (1) = 0.0, P = 0.995
Education:				χ² (2) = 3.76, P = 0.153
Basic or no HS degree	187 (24.3)	25 (24.3)	162 (24.3)
HS without college degree	419 (54.4)	64 (62.1)	355 (53.2)
Advanced education	146 (19.0)	13 (12.6)	133 (19.9)
Body mass index, mean (SD)	29.2 (6.1)	29.7 (6.3)	29.2 (6.1)	t = 0.77, P = 0.444
Diabetes	264 (34.3)	42 (40.8)	222 (33.3)	χ² (1) = 2.41, P = 0.120
History of heart failure	101 (13.1)	17 (16.5)	84 (12.6)	χ² (1) = 1.28, P = 0.258
Hypertension	458 (59.5)	70 (68.0)	388 (58.2)	χ² (1) = 4.56, P = 0.033
Prior MI	187 (24.3)	22 (21.4)	165 (24.7)	χ² (1) = 0.41, P = 0.524
Prior stroke	70 (9.1)	13 (12.9)	57 (8.7)	χ² (1) = 1.80, P = 0.180
Current smoker	254 (33.0)	46 (44.7)	208 (31.2)	χ² (1) = 7.34, P = 0.007
Social characteristics
Live alone	322 (41.8)	46 (44.7)	276 (41.4)	χ² (1) = 0.32, P = 0.570
Social support	356 (46.2)	54 (52.4)	302 (45.3)	χ² (1) = 1.84, P = 0.176
Psychological characteristics
Depression				χ² (2) = 16.7, P > 0.001
Major depression	398 (51.7)	69 (67.0)	329 (49.3)
Minor depression	348 (45.2)	28 (27.2)	320 (48.0)
Dysthymia	24 (3.1)	6 (5.8)	18 (2.7)
Psychosocial measures
Baseline Depression Symptom Severity (BDI), mean (SD)	17.7 (7.8)	22.4 (9.3)	17.0 (7.4)	t = 6.62, P < 0.001
Baseline Perceived Social Support (ESSI), mean (SD)	24.5 (6.4)	22.9 (7.0)	24.7 (6.3)	t = -2.74, P = 0.006
Baseline Depression Symptom (HAM-D), mean (SD)	17.9 (6.3)	20.9 (6.5)	17.4 (6.1)	t = 5.07, P < 0.001

¹Except where mean (SD) is noted. BDI: Beck Depression Inventory; ESSI: ENRICHD Social Support Inventory; HAM-D: Hamilton Depression Rating Scale; HS: High school; TRD: Treatment resistant depression; MI: Myocardial infarction.

Citation: Banankhah SK, Friedmann E, Thomas S. Effective treatment of depression improves post-myocardial infarction survival. World J Cardiol 2015; 7(4): 215-223
URL: https://www.wjgnet.com/1949-8462/full/v7/i4/215.htm
DOI: https://dx.doi.org/10.4330/wjc.v7.i4.215