Role of Helicobacter pylori infection in pathogenesis of atherosclerosis

Table 2 Mechanisms of Helicobacter pylori related atherosclerosis

Induction of inflammatory response secondary to chronic infectious state

Endothelial damage

Chronic low grade activation of coagulation cascade

Dysregulation of lipid metabolism resulting in increased total cholesterol and triglyceride levels and reduced high density lipoprotein levels

Hyperhomocysteinaemia

While the proponents support the possible association[52,70,104], the opponents refute this hypothesis[46,71,105].