Cardiac and non-cardiac causes of T-wave inversion in the precordial leads in adult subjects: A Dutch case series and review of the literature

Figure 2 Patient 2. An electrocardiographic (ECG) tracing, illustrating the negative T-wave with minimal ST segment elevation in the precordial leads V_1-4, of a 82-year-old-female patient presented with acute coronary syndrome due to non ST elevation myocardial infarction. Her previous medical history included hormonal substitution for hypothyroidism, ablatio retinae, polymylagia rheumatica, arterial hypertension, mild concentric left ventricular hypertrophy, aortic valvular stenosis with a peak gradient of 18 mmHg and mild aortic regurgitation grade 2/4. In 2011, analysis with ambulatory ECG recording for a syncopal attack revealed no abnormalities. Transthoracic echocardiography demonstrated apicoinferior hypokinesia. The patient was treated medically and remained free of symptoms. Her maintenance drug therapy consisted of BB, aspirin (ASA), clopidogrel, Angiotensin-II antagonist, prednisolon, diuretic and statin.