Current status of high on-treatment platelet reactivity in patients with coronary or peripheral arterial disease: Mechanisms, evaluation and clinical implications

Table 2 Highlighted multicenter randomized control trials investigating platelet function tests-guided antiplatelet therapy

Study	Gravitas	Arctic	Trigger-PCI
Study population (n)	2214	2440	423
PFT assay	VerifyNow	VerifyNow	VerifyNow
High-dose clopidogrel	100%	80%	-
High-dose Aspirin	-	45%	-
Prasugrel	-	12%	100%
Results (primary endpoint)	2.3% vs 2.3%	31.1% vs 34.6%	0.0% vs 0.5%

PFT: Platelet function tests; PCI: Percutaneous coronary intervention.