Current status of high on-treatment platelet reactivity in patients with coronary or peripheral arterial disease: Mechanisms, evaluation and clinical implications

Table 1 Common platelet function assays

Test	LTA	VASP	VerifyNow
Function	Increase in light transmittance	Flow cytometric measurement of VASP phosphorylation	Measurement of platelet-induced aggregation to fibrinogen-coated beads
Receptor	P2Y1 and P2Y12	P2Y12	P2Y12
Results	MPA	PRI	PRU
Cut-off value	> 46%	> 50%	230-240

LTA: Light transmission aggregometry; VASP: Vasodilator-stimulated phosphoprotein phosphorylation; MPA: Maximal platelet aggregation; PRI: Platelet reactivity index; PRU: P2Y12 reaction units.