Renal function assessment in atrial fibrillation: Usefulness of chronic kidney disease epidemiology collaboration vs re-expressed 4 variable modification of diet in renal disease

Table 4 Calibration and discrimination abilities of the re-expressed four variables Modification of Diet in Renal Disease and the new Chronic Kidney Disease Epidemiology Collaboration equations

			MDRD-4	CKD-EPI	P value
Composite endpoint	Calibration, χ2 (P value)		1.7 (0.79)	3.5 (0.48)
	c-statistic (95%CI)	eGFR continuous	0.683 (0.629-0.737)	0.695 (0.643-0.747)	0.748
		eGFR categorical	0.632 (0.600-0.664)	0.639 (0.607-0.670)	0.452
Major bleeding	Calibration, χ2 (P value)		5.9 (0.20)	5.4 (0.25)
	c-statistic (95%CI)	eGFR continuous	0.666 (0.581-0.751)	0.677 (0.596-0.759)	0.8548
		eGFR categorical	0.550 (0.443-0.658)	0.571 (0.465-0.679)	0.7872
Thromboembolism	Calibration, χ2 (P value)		0.13 (0.99)	1.9 (0.76)
	c-statistic (95%CI)	eGFR continuous	0.616 (0.584-0.648)	0.644 (0.612-0.675)	0.2736
		eGFR categorical	0.617 (0.585-0.649)	0.622 (0.590-0.654)	0.7582
All-cause mortality	Calibration, χ2 (P value)		0.83 (0.94)	1.5 (0.82)
	c-statistic (95%CI)	eGFR continuous	0.715 (0.684-0.744)	0.722 (0.691-0.750)	0.5227
		eGFR categorical	0.679 (0.647-0. 709)	0.678 (0.646-0.708)	0.911

eGFR: Estimated glomerular filtration rate; CKD-EPI: Chronic Kidney Disease Epidemiology Collaboration; MDRD-4: 4-variable Modification of Diet in Renal Disease Study equation.