Retrospective Cohort Study
Copyright ©The Author(s) 2015.
World J Cardiol. Oct 26, 2015; 7(10): 685-694
Published online Oct 26, 2015. doi: 10.4330/wjc.v7.i10.685
Table 3 Unadjusted and adjusted effect (HR) on outcomes of categorical estimated glomerular filtration rate determined by the re-expressed four variables Modification of Diet in Renal Disease and the new Chronic Kidney Disease Epidemiology Collaboration equations
MDRD-4
CKD-EPI
n (%)Unadjusted HR (95%CI)Adjusted HR (95%CI)Unadjusted HR (95%CI)Adjusted HR (95%CI)
Composite endpoint, 98 (10.8)≥ 601.00 (Reference)
30-592.43 (1.592-3.703)1.71 (1.11-2.78)2.51 (1.642-3.827)1.81 (1.1-2.8)
P < 0.0001P = 0.02P < 0.0001P = 0.02
< 306.99 (3.585-13.649)3.3 (1.6-6.9)7.4 (3.871-14.125)3.6 (1.8-7.4)
P < 0.0001P = 0.001P < 0.0001P < 0.0001
Major bleeding, 30 (3.3)≥ 601.00 (Reference)
30-591.53 (0.715-3.260)1.012 (0.46-2.25)1.87 (0.883-3.948)1.22 (0.58-2.75)
P = 0.30P = 0.95P = 0.1P = 0.58
< 303.56 (0.811-15.580)1.03 (0.22-4.95)3.65 (0.827-16.074)1.1 (0.25-5.35)
P = 0.09P = 0.93P = 0.08P = 0.9
Thromboembolism, 18 (2)≥ 601.00 (Reference)
30-592.04 (0.734-5.649)1.43 (0.49-4.15)2.13 (0.767-5.917)1.43 (0.50-4.25)
P = 0.17P = 0.15P = 0.15P = 0.50
< 308.01 (1.664-38.555)5.1 (1.04-25.4)7.84 (1.625-37.825)5 (1.0-24.9)
P = 0.009P = 0.045P = 0.01P = 0.04
All-cause mortality, 60 (6.6)≥ 601.00 (Reference)
30-593.34 (1.909-5.827)2.64 (1.4-2.7)3.14 (1.793-5.481)2.44 (1.3-4.5)
P < 0.0001P = 0.002P < 0.0001P = 0.005
< 3010.64 (4.843-23.359)4.9 (2.0-11.9)10.89 (5.122-23.166)5.2 (2.2-12.3)
P < 0.0001P < 0.0001P < 0.0001P < 0.0001

  • Citation: Abumuaileq RRY, Abu-Assi E, López-López A, Raposeiras-Roubin S, Rodríguez-Mañero M, Martínez-Sande L, García-Seara FJ, Fernandez-López XA, González-Juanatey JR. Renal function assessment in atrial fibrillation: Usefulness of chronic kidney disease epidemiology collaboration vs re-expressed 4 variable modification of diet in renal disease. World J Cardiol 2015; 7(10): 685-694
  • URL: https://www.wjgnet.com/1949-8462/full/v7/i10/685.htm
  • DOI: https://dx.doi.org/10.4330/wjc.v7.i10.685