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©2014 Baishideng Publishing Group Inc.
World J Cardiol. Jul 26, 2014; 6(7): 638-652
Published online Jul 26, 2014. doi: 10.4330/wjc.v6.i7.638
Published online Jul 26, 2014. doi: 10.4330/wjc.v6.i7.638
n | State 3 respiration (nmol O2/min per milligram) | State 4 respiration (nmol O2/min per milligram) | RCI (state3 rate): (state 4 rate) | Leak respiration(nmol O2/min per milligram) | Stimulation by cytochrome c % | |
Control | ||||||
Before ischemia | 4 | 6.4 ± 1.1 | 0.5 ± 0.1 | 12.5 ± 2.7 | 0.15 ± 0.07 | 6.0 ± 10.0 |
Ischemia 45 min | 8 | 3.5 ± 1.4ac | 0.9 ± 0.3a | 4.4 ± 2.5a | 0.32 ± 0.14a | 10.0 ± 6.0 |
Reperfusion 60 min | 4 | 2.6 ± 1.3ac | 0.9 ± 0.3a | 3.2 ± 2.1a | 0.43 ± 0.29 | 28.0 ± 16.0 |
A-705239 treated hearts | ||||||
Before ischemia | 4 | 6.8 ± 1.3 | 0.6 ± 0.1 | 12.4 ± 1.1 | 0.12 ± 0.06 | 16.0 ± 9.0 |
Ischemia 45 min | 9 | 5.0 ± 0.8ac | 0.6 ± 0.2 | 8.2 ± 2.3ac | 0.20 ± 0.14a | 15.0 ± 13.0 |
Reperfusion 60 min | 5 | 4.2 ± 1.2ac | 0.7 ± 0.2 | 6.4 ± 2.7a | 0.26 ± 0.24 |
- Citation: Neuhof C, Neuhof H. Calpain system and its involvement in myocardial ischemia and reperfusion injury. World J Cardiol 2014; 6(7): 638-652
- URL: https://www.wjgnet.com/1949-8462/full/v6/i7/638.htm
- DOI: https://dx.doi.org/10.4330/wjc.v6.i7.638