Significance of lead aVR in acute coronary syndrome

Table 2 Current evidence concerning the prognostic significance of ST-segment elevation or depression in lead aVR in acute coronary syndrome

Type of ACS	Findings of previous studies
NSTE-ACS	ST-segment elevation in lead aVR was independently associated with increased in-hospital mortality[4]
	Neither minor (0.05-0.1 mV) nor major (> 0.1 mV) ST-segment elevation in lead aVR was an independent predictor of in-hospital or 6-mo mortality[5]
	ST-segment depression ≥ 0.05 mV in any lead plus ST-segment elevation ≥ 0.1 mV in lead aVR was independently associated with increased in-hospital and 1-year cardiovascular deaths[6]
	ST-segment elevation ≥ 0.05 mV in lead aVR was an independent predictor of 90-d adverse outcomes, including death, myocardial infarction, or urgent revascularization[8]
Anterior wall STEMI	U-shaped relationship between ST-segment shift in lead aVR and 30-d mortality was observed[18]
Non-inferior wall STEMI	ST-segment depression ≥ 0.1 mV in lead aVR was independently associated with increased 90-d mortality[19]
Inferior wall STEMI	ST-segment elevation ≥ 0.1 mV in lead aVR was independently associated with increased 30-d mortality[18]
	ST-segment elevation ≥ 0.1 mV in lead aVR was independently associated with increased 90-d mortality[19]

ACS: Acute coronary syndrome; NSTE: Non ST-segment elevation; STEMI: ST-segment elevation myocardial infarction.