Effect of genetic factors on the association between coronary artery disease and PTPN22 polymorphism

Table 3 Proportion of carriers of *T allele of PTPN22 in relation to the presence of the adenosine deaminase locus 2 *2 allele of adenosine deaminase locus 2 polymorphism

	Proportion of carriers of *T allele of PTPN22		Total of subjects, n
Non diabetic subjects with CAD
ADA2 *1/*1 genotype	8.3%		84
Carriers of ADA2 *2 allele	20.8%		48
Non diabetic subjects with cardiovascular diseases without CAD
ADA2 *1/*1 genotype	6.7%		75
Carriers of ADA2 *2 allele	2.2%		46
Blood donors
ADA2 *1/*1 genotype	4.5%		88
Carriers of ADA2 *2 allele	5.1%		59
Statistical analysis		χ2 test of independence
	χ2	df	P
ADA2 *1/*1 genotype	1.024	2	0.599
Carriers of ADA2 *2 allele	11.747	2	0.003

CAD: Coronary artery disease; ADA₂: Adenosine deaminase locus 2.