Effect of genetic factors on the association between coronary artery disease and PTPN22 polymorphism

Table 1 Proportion of *T allele of PTPN22 in relation to the presence of *A allele of acid phosphatse locus 1 polymorphism

	Proportion of carriers of *T allele of PTPN22		Total of subjects, n
Non diabetic subjects with CAD
Subjects carrying the *A allele	19.3%		62
Other ACP1 genotypes	7.0%		71
Non diabetic subjects with cardiovascular diseases without CAD
Subjects carrying the *A allele	3.4%		59
Other ACP1 genotypes	6.3%		63
Blood donors
Subjects carrying the *A allele	7.2%		138
Other ACP1 genotypes	4.6%		131
Statistical analysis		χ2 test of independence
	χ2	df	P
Carriers of *A allele	10.598	2	0.005
Other ACP1 genotypes	0.998	2	0.742

CAD: Coronary artery disease; ACP₁: Acid phosphatse locus 1.