Molecular phenotypes of human parvovirus B19 in patients with myocarditis

Figure 4 Genotype specific myocardial B19V loads of patients with chronic myocarditis. A: Prevalence of B19V-genotype 1 (B19V-1) and B19V-2 in endomyocardial biopsies of patients with myocarditis [inflammatory cardiomyopathy (iCMP), grey columns] and dilated cardiomyopathy (DCM, white columns). Patient number is given in %; B: qPCR of myocardial of B19V-1 and B19V-2 loads in endomyocardial biopsies (EMBs); C: B19V genotype-specific myocardial viral loads in EMBs of patients with chronic myocarditis (iCMP, white columns) and DCM (grey columns) determined by qPCR. One-way Anova was highly significant (P < 0.0001). P < 0.05 is statistically significant (two-tailed T-test). qPCR: Quantitative real-time polymerase chain reaction.