Mitochondria-targeted agents: Future perspectives of mitochondrial pharmaceutics in cardiovascular diseases

doi:10.4330/wjc.v6.i10.1091

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Oct 26, 2014 (publication date) through Jul 24, 2024

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Oct 26, 2014; 6(10): 1091-1099
Published online Oct 26, 2014. doi: 10.4330/wjc.v6.i10.1091

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Figure 2 Factors that form and attenuate (antioxidants) reactive oxygen species in mitochondria. SDH: Succinate dehydrogenase; αKGDH: Alpha ketoglutarate dehydrogenase; MAO: Monoamine oxidase; Trx: Thioredoxins; Prx: Peroxiredoxin; OXPHOS: Oxidative phosphorylations; TNF-α: Tumor necrosis factor-alpha; GSH: Reduced glutathione; MnSOD: Manganese containing superoxide dismutase; GPx1: Glutathione peroxidase; CoQ₁₀: Co-enzyme Q₁₀.

Citation: Ajith TA, Jayakumar TG. Mitochondria-targeted agents: Future perspectives of mitochondrial pharmaceutics in cardiovascular diseases. World J Cardiol 2014; 6(10): 1091-1099
URL: https://www.wjgnet.com/1949-8462/full/v6/i10/1091.htm
DOI: https://dx.doi.org/10.4330/wjc.v6.i10.1091