BLEED-Myocardial Infarction Score: Predicting mid-term post-discharge bleeding events

doi:10.4330/wjc.v5.i6.196

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World Journal of Cardiology

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1949-8462

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Cardiol. Jun 26, 2013; 5(6): 196-206
Published online Jun 26, 2013. doi: 10.4330/wjc.v5.i6.196

Table 3 Description of derivation and validation samples

Characteristic	Derivation sample (n = 1050)	Validation sample (n = 852)
Age (yr)	67.9 ± 13.5	67.9 ± 13.6
Male gender	686 (64.7)	578 (68.0)
Type of myocardial infarction
STEMI	42.1%	38.8%
NSTEMI	57.9%	61.2%
Diabetes mellitus	380 (35.9)	266 (31.2)
Previous hypertension	796 (75.2)	631 (74.2)
Hyperlipidemia	59629 (56.3)	475 (59.6)
Smoking habits	287 (27.1)	281 (33.1)
Previously known coronary disease	283 (26.7)	243 (28.6)
History of stroke/TIA	94 (9.0)	77 (9.1)
Atrial fibrillation at admission	144 (13.7)	99 (12.4)
Admission killip class	1.40 ± 0.6	1.36 ± 0.7
Maximum killip class	1.56 ± 0.8	1.46 ± 0.8
Average number of vessels with significant lesions	1.60 ± 0.97	1.54 ± 0.99
GFR at admission	68.6 ± 38.4	72.6 ± 32.0
BUN at admission (mmol/L)	9.58 ± 6.81	8.85 ± 6.20
Hemoglobin at admission (mg/dL)	13.3 ± 2.1	13.8 ± 6.14
NT-proBNP at admission (ng/L)	4202 ± 13400	6393 ± 15950
Submitted to revascularization procedures	645 (61.4)	663 (77.8)
Clinically significant bleeding during hospitalization	87 (8.3)	55 (6.5)
Average GRACE score for intrahospital mortality	153.9 (P₂₅ 124; P₅₀ 151; P₇₅ 179)	145.6 (P₂₅ 114; P₅₀ 143; P₇₅ 173)
Average GRACE score for 6-mo mortality	128.0 (P₂₅ 102; P₅₀ 125; P₇₅ 149)	121.0 (P₂₅ 94; P₅₀ 118; P₇₅ 145)
Moderate-severe left ventricular systolic dysfunction	19.50%	23.00%
Discharged on dual anti-platelet therapy	818 (89.2)	723 (90.6)
Discharged on anticoagulant treatment	36 (3.9)	37 (4.6)
Intrahospital mortality	8.60%	6.10%
Post-discharge mortality (mo)	165 (16.5) (Follow-up: 19.9 ± 6.7)	88 (11.0) (Follow-up: 13.4 ± 8.1)
Bleeding events during follow-up (mo)	62 (6.8) (Follow-up: 19.9 ± 6.7)	60 (7.5) (Follow-up: 13.4 ± 8.1)

Data are expressed as absolute numbers (percentage) or mean ± SD. TIA: Transient ischaemic attack; BUN: Blood urea nitrogen; CRP: C-reactive protein; NSTEMI: Non-ST elevation myocardial infarction; STEMI: ST elevation myocardial infarction.

Citation: Barra S, Providência R, Caetano F, Almeida I, Paiva L, Dinis P, Leitão Marques A. BLEED-Myocardial Infarction Score: Predicting mid-term post-discharge bleeding events. World J Cardiol 2013; 5(6): 196-206
URL: https://www.wjgnet.com/1949-8462/full/v5/i6/196.htm
DOI: https://dx.doi.org/10.4330/wjc.v5.i6.196