Ultrasound-assessed non-culprit and culprit coronary vessels differ by age and gender

Table 2 Age- and gender-related differences of plaque burden and plaque components in vessels containing non-culprit or culprit lesions (mean ± SD)

Plaque component	Patients in the lowest age tertile			Patients in the middle age tertile			Patients in the highest age tertile			P value1	P value2
	Male	Female	P value	Male	Female	P value	Male	Female	P value
Non-culprit vessels
Segments available for analysis	n = 154	n = 44		n = 159	n = 54		n = 140	n = 67
Plaque burden, %	37 ± 12	30 ± 9	< 0.001	42 ± 11	35 ± 12	< 0.001	46 ± 10	40 ± 11	< 0.001	< 0.001	< 0.001
Fibrous volume, %	53 ± 12	44 ± 20	< 0.001	51 ± 12	54 ± 13	0.161	52 ± 11	53 ± 12	0.947	0.949	0.005
Fibro-fatty volume, %	13 ± 11	17 ± 19	0.966	11 ± 9	17 ± 15	0.053	13 ± 9	12 ± 10	0.365	0.992	0.060
NC volume, %	18 ± 8	15 ± 10	0.033	21 ± 9	16 ± 10	< 0.001	20 ± 8	19 ± 9	0.646	0.13	0.017
DC volume, %	17 ± 14	24 ± 22	0.324	17 ± 12	13 ± 14	0.003	15 ± 10	16 ± 12	0.814	0.323	0.028
Lumen volume, mm3	398 ± 182	342 ± 115	0.053	348 ± 133	308 ± 130	0.057	310 ± 133	332 ± 127	0.267	< 0.001	0.815
Culprit vessels
Segments available for analysis	n = 22	n = 5		n = 19	n = 3		n = 16	n = 8
Plaque burden, %	48 ± 6	44 ± 18	0.376	43 ± 11	47 ± 14	0.578	51 ± 9	49 ± 8	0.724	0.523	0.449
Fibrous volume, %	57 ± 9	58 ± 8	0.795	51 ± 10	67 ± 12	0.026	44 ± 12	57 ± 11	0.024	< 0.001	0.727
Fibro-fatty volume, %	13 ± 9	13 ± 6	0.683	9 ± 5	8 ± 2	0.562	7 ± 5	11 ± 7	0.069	0.006	0.561
NC volume, %	19 ± 8	19 ± 7	0.930	23 ± 9	17 ± 8	0.285	28 ± 7	20 ± 7	0.018	0.003	0.697
DC volume, %	11 ± 8	10 ± 8	0.851	17 ± 8	8 ± 7	0.113	22 ± 12	13 ± 12	0.040	0.001	0.655
Lumen volume, mm3	340 ± 144	398 ± 340	0.541	385 ± 171	236 ± 133	0.168	271 ± 82	307 ± 116	0.394	0.201	0.505

¹P value for trend across age groups in men. ¹P value was calculated using linear regression;

²P value for trend across age groups in women. P value was calculated using linear regression. DC: Dense calcium; NC: Necrotic core.