Positive influence of aspirin on coronary endothelial function: Importance of the dose

Table 4 Hemodynamics and angiographic results between groups Ia and Ib (mean ± SE)

	Group Ia	Group Ib	P value
	(n =50)	(n = 13)
Baseline mean BP (mmHg)	108 ± 2	105 ± 3	NS
Baseline heart rate (/min)	67 ± 2	65 ± 3	NS
Coronary diameter
Baseline (mm)	3.23 ± 0.08	3.14 ± 0.16	NS
ACh at 3 μg/min (mm)	3.32 ± 0.08	3.05 ± 0.17	NS
(% change)	2.4 ± 0.9	-0.6 ± 1.8	NS
ACh at 30 μg/min (mm)	3.32 ± 0.08	3.05 ± 0.17	NS
(% change)	2.6 ± 1.1	-3.8 ± 2.9	0.0123
Nitroglycerin (mm)	3.67 ± 0.08	3.65 ± 0.16	NS
(% change)	13.6 ± 1.1	15.4 ± 2.2	NS
Coronary blood flow
Baseline (mL/min)	91.0 ± 4.6	76.8 ± 9.1	NS
ACh at 3 μg/min (mL/min)	137.7 ± 9.5	106.8 ± 18.7	NS
(% change)	53.4 ± 6.8	37.0 ± 13.4	NS
ACh at 30 μg/min (mm)	195.2 ± 15.9	188.6 ± 31.1	NS
(% change)	125.3 ± 16.2	141.9 ± 31.7	NS
Coronary flow reserve	3.4 ± 0.2	3.7 ± 0.3	NS

BP: Blood pressure; ACh: Acetylcholine; NS: Not significant.