Gender gap in acute coronary heart disease: Myth or reality?

Table 6 Mortality rates in male and female patients with coronary artery disease at admission, at thirty days and after one-year of follow-up

Author study/date	Design	Study population	Patients		Age (mean, yr)		P	Mortality < admission (%)		P	Mortality < 30 d (%)		P	Mortality < 1 year (%)		P
			Men	Women	Men	Women		Men	Women		Men	Women		Men	Women
Lansky et al[22] 2005	RCT	AMI + PTCA	1520	562	57.0	66.0	< 0.001	1.0	3.4	0.0003	1.1	4.6	< 0.001	3.0	7.6	< 0.001
Singh et al[79] 2008	Retro cohort	PCI	7616	3365	64.7	69.4	0.48	1.8	2.5	0.38	2	3	0.25	4	4	0.490
Alfredsson et al[11] 2007	Pros cohort	Unstable/NSTEMI	34 020	19 761	69	73	< 0.001	5	7		7	9		16	19
Setoguchi et al[31] 2008	Pros cohort	AMI	317	1308	80	82	< 0.001	14.5	13.9		9.8	8.6		21.5	18.2
														24.33	25.03
Matsui et al[26] 2002	RCT	MI	346	136	62.9	70.4		4	4	0.851	4	10	0.013
Uva et al[35] 2009	RCT	CABG	1485	481	64.7	69.0	0.001	0.8	2	0.01	1.2	2.3	0.09
Toumpoulis et al[34] 2006	Pros cohort	CABG	2598	1162	63.2	66.2	< 0.001	2.7	2.9	0.639	3.7	3.9	0.747
Moriel et al[28] 2005	Pros cohort	ACS	820	511	78	79	0.12	7	12	0.007				191	211	0.480
Herlitz et al[18] 2009	Retro cohort	AMI	835	588	72.7	79.2	< 0.0001	12	14	NS				18	22	0.040
Lawesson et al[24] 2010	Retro cohort	STEMI aged < 46	1748	384	40.8	40.4	0.14	1.0	2.9	0.005				2.2	3.7	0.010
Berger et al[10] 2006	Pros cohort	PCI	2953	1331	61.9	66.8	< 0.001	0.5	0.5	0.918				8.92	102	0.197
Liu et al[25] 2008	Pros cohort	STEMI + PCI	143	116	68.1	68.7	0.61	2.8	5.2					0	3.4
Anand et al[9] 2005	Trial	ACS	7726	4836	62.7	66.5	0.0001				4.9	4.4	0.235	11.1	9.7	0.040
Tizón-Marcos et al[33] 2009	RCT	PCI	1050	298	59.7	62.5	< 0.0001				0.2	0	1.00	0.8	1.0	0.720
Tillmanns et al[32] 2005	Pros cohort	STEMI	513	178	60	66	< 0.0001				6	6.2	NS	9	12.5	0.600
														122	182	0.070
Lansky et al[67] 2009	RCT	PCI	687	314	61.8	65.9	< 0.0001				0	0		1.0	0.3	0.447
Koch et al[20] 2003	Pros cohort	CABG	1588	460							2.5	3.4	0.29	4.21	7.11	0.020
														15.84	19.64	0.030
Lagerqvist et al[21] 2001	RCT	AMI	1708	749	64	68	< 0.001							5.7	7.2	NS
Chiu et al[13] 2004	Pros cohort	PCI	12 738	5301	62.3	66.5	< 0.001							5	7	< 0.001

¹After 6 mo;

²After 3 years;

³After 4 years;

⁴After 5 years;

⁵Adjusted for age, diabetes, smoking, history of cardiovascular disease, increased cardiac enzymes, region and received therapy. MI: Myocardial infarction; CABG: Coronary artery bypass grafting; PCI: Percutaneous coronary intervention; ACS: Acute coronary syndrome; STEMI: ST elevation MI; NS: Not significant.