Gender gap in acute coronary heart disease: Myth or reality?

Table 5 Percentage of peri-procedural complications during index admission stratified by gender

Author study/date	Design	Study population	Patients		Age (mean, yr)		P	Complications < admission (%)			P
			Men	Women	Men	Women			Men	Women
Lansky et al[22] 2005	RCT	AMI + PTCA	1520	562	57.0	66.0	< 0.001	MACE	3.2	6.4	0.002
								Bleeding	2.0	5.2	0.0003
Lansky et al[67] 2009	RCT	PCI	687	314	61.8	65.9	< 0.0001	MACE1	1.3	3.2	0.0766
								Vascular1	0.6	1.0	0.6844
								MI1	1.0	2.9	0.0526
Tizón-Marcos et al[33] 2009	RCT	PCI	1050	298	59.7	62.5	< 0.0001	MACE1	3.9	3.4	0.86
								Bleeding1	1.1	2.4	0.16
								MI1	3.5	3.0	0.86
Thompson et al[53] 2006	Pros cohort	PCI	807	359	61.7	67.7	< 0.0001	MACE	2.7	3.9	0.29
								Vascular	4.2	12.0	< 0.0001
Jibran et al[81] 2010	Retro cohort	ACS + PCI	331	137	60.7	66.1	< 0.0001	MACE1	3.9	2.9	0.8
								Access site1	1.5	6.2	0.02
								MI1	1.5	0.7	1.0
Duvernoy et al[43] 2010	Pros cohort	PCI	14 848	7877	61.9	66.9	< 0.001	MACE	4.48	5.19	< 0.001
								Vascular	1.02	3.34	< 0.001
								MI	1.60	1.66	0.70
Bufe et al[62] 2010	Pros cohort	STEMI + PCI	376	124	58	65	< 0.001	Shock	10.1	11.3	0.838
								Renal failure	1.3	1.6	0.835
Reynolds et al[30] 2007	RTC	MI	12 498	4090	59.5	67.0	< 0.001	CVA1	0.2	0.6	< 0.01
								Heart failure	4.0	6.7	< 0.001
								Re-MI	2.7	3.5	0.004
Matsui et al[26] 2002	Retro cohort	AMI	346	136	62.9	70.4		Heart failure	16	26	0.013
								Re-MI	5	6	0.568
Moriel et al[28] 2005	Pros cohort	ACS	820	511	78	79	0.12	CVA	2	1	0.79
								Heart failure	21	21	0.86
								Re-MI	15	14	0.61
Uva et al[35] 2009	RCT	CABG	1485	481	64.7	69.0	0.001	MACE	3.9	6.6	NS
								CVA	0.7	1.2	0.2
								MI	0.7	1.3	0.08
Herlitz et al[18] 2009	Retro cohort	AMI	835	588	72.7	79.2	< 0.0001	Re-MI	4	2	0.02
Toumpoulis et al[34] 2006	Pros cohort	CABG	2598	1162	63.2	66.2	< 0.001	CVA	2.8	4.2	NS
								Bleeding	1.8	1.5	0.592
								MI	0.6	0.7	0.657
Liu et al[25] 2008	Pros cohort	STEMI + PCI	143	116	68.1	68.7	0.61	MACE	4.2	6.0	0.50
Berger et al[10] 2006	Pros cohort	PCI	2953	1331	61.9	66.8	< 0.001	MACE	2.9	3.0	0.922
								CVA	0.1	0.2	0.905
								MI	1.6	1.7	NS
								Access site	0.0	0.3	0.018
Chiu et al[13] 2004	Pros cohort	PCI	12 738	5301	62.3	66.5	< 0.001	Transfusion	4	12	< 0.001
								Haematoma	5	6	0.568
Setoguchi et al[31] 2008	Pros cohort	AMI	317	1308	80	82	< 0.001	CVA	3	4	0.57
Singh et al[79] 2008	Retro cohort	PCI	7616	3365	64.7	69.4	0.48	CVA	0.5	0.9	0.29
								MI	1.1	1.4	0.44
Tillmanns et al[32] 2005	Pros cohort	STEMI	513	178	60	66	< 0.0001	Re-MI	3	2	NS

¹After 30 d. MI: Myocardial infarction; CABG: Coronary artery bypass grafting; PCI: Percutaneous coronary intervention; ACS: Acute coronary syndrome; STEMI: ST elevation MI; NS: Not significant; CVA: Cerebrovascular accident; MACE: Major adverse cardiac events.