Gender gap in acute coronary heart disease: Myth or reality?

Table 3 Extent of coronary artery disease stratified by gender

Author study/date	Design	Study population	Patients		Age (mean, yr)		P	1 vessel disease (%)		P	3 vessel disease (%)		P
			Men	Women	Men	Women		Men	Women		Men	Women
Lansky et al[22] 2005	RCT	AMI + PTCA	1520	562	57.0	66.0	< 0.001	51.1	51.6	NS	15.7	15.3	NS
Lansky et al[67] 2009	RCT	PCI	687	314	61.8	65.9	< 0.0001	61.3	74.2	< 0.0001	11.5	4.5	0.0002
Tizón-Marcos et al[33] 2009	RCT	PCI	1050	298	59.7	62.5		58	65	0.066	9.8	7.4	0.066
Hirakawa et al[19] 2007	Pros cohort	AMI	2048	566	62.92	71.08	< 0.01	60.1	56.0	< 0.05	34.81	40.11	< 0.05
Mueller et al[55] 2002	Pros cohort	MI	1033	417	64	68	0.01	24	26	0.45	42	29	0.01
Duvernoy et al[43] 2010	Pros cohort	PCI	14 848	7877	61.9	66.9	< 0.001	49.4	55.0	< 0.001	22.8	18.0	< 0.001
Liu et al[25] 2008	Pros cohort	STEMI + PCI	143	116	68.1	68.7	0.61	14.7	10.3	0.29	48.2	61.2	0.03
Jibran et al[81] 2010	Retro cohort	ACS + PCI	331	137	60.7	66.1	< 0.00001	41.1	48.9	0.3	22.7	12.4	0.3
De Luca et al[41] 2004	Pros cohort	STEMI	1195	353	59	66	< 0.001	47.9	43.8	NS	20.7	22.3	NS
Bufe et al[62] 2010	Pros cohort	STEMI + PCI	376	124	58	65	< 0.001	48.1	54.0	0.031	24.2	21.8	0.667
Lawesson et al[24] 2010	Retro cohort	STEMI aged < 46	1748	384	40.8	40.4	0.14	59.3	72.9	< 0.001	33.6	19.2	< 0.001
Berger et al[10] 2006	Pros cohort	PCI	2953	1331	61.9	66.8	< 0.001	48	50	0.195	18	17	NS
Toumpoulis et al[34] 2006	Pros cohort	CABG	2598	1162	63.2	66.2	< 0.001	4.6	7.3	0.001	73.7	69.3	0.005
Tillmanns et al[32] 2005	Pros cohort	STEMI	513	178	60	66	< 0.0001	43	44	NS	571	561	NS
Vakili et al[57] 2001	Retro cohort	PTCA first MI	727	317	59	65	< 0.005	56	59	NS	15	12	NS

¹More than single vessel disease. MI: Myocardial infarction; CABG: Coronary artery bypass grafting; STEMI: ST elevation MI; NS: Not significant.