Advantages and disadvantages of biodegradable platforms in drug eluting stents

Table 3 Comparison between published trials of biodegradable eluting stents

Name	Stent design	Cardiac death	Cardiac death or MI	MI	TVR	TLR
LEADERS[28]	Biomatrix	2.1	6.7	5.8	7.8	6.5
	Cypher	2.7	6.6	4.6	9.9	7.4
	Nobori	0.0	-	4.7	7.1	0.0
NOBORI[34]	Taxus	0.0	-	8.6	14.3	2.9
ISAR-TEST-3[35]	Biodegradable polymer stent	2.0	2.5	1.5	-	5.9
	Permanent polymer sirolimus	2.0	3.5	2.0	-	7.9
	Polymer free sirolimus	2.0	4.0	2.5	-	12.9
ISAR-TEST-4[36]	Biodegradable polymer	2.8	6.3	4.3	13.7	8.8
	Control1	3.2	6.2	4.1	13.9	9.4
EUCATAX[39]	PES	1.9	4.7	2.8	8.2	6.1
	BMS	1.9	4.3	2.4	15.0	12.6

¹Control reflects results of Cypher (Cordis, Florida, USA) or Xience (Abbott Vascular, Abbott Park, IL, USA). MI: Myocardial infarction; TVR: Target vessel revascularization; TLR: Target lesion revascularization; ISAR: Individualized Drug Eluting Stent System to Abrogate Restenosis.